Skin & Cosmetic Peptides
Peptides used in skincare for anti-aging, wrinkle reduction, collagen stimulation, and skin repair. From copper peptides to neurotransmitter-inhibiting peptides, these compounds are backed by varying levels of clinical evidence.
Category Overview
Cosmetic peptides are among the safest peptides available because they are applied topically rather than injected. They work by penetrating the outer skin layers to stimulate collagen production, reduce inflammation, or modulate muscle contractions that cause wrinkles.
GHK-Cu (copper peptide) stands out as the most researched cosmetic peptide with over 60 published studies. Matrixyl is the most commercially successful, found in thousands of skincare products. Argireline offers a non-invasive alternative to Botox for expression lines.
Oral collagen peptides represent a different approach — providing building blocks for skin collagen from the inside. Multiple randomized controlled trials support their efficacy for skin elasticity and hydration.
All Skin & Cosmetic Peptides
The gold standard of cosmetic peptides. Stimulates collagen synthesis, promotes wound healing, has antioxidant and anti-inflammatory effects. Extensively researched with strong evidence for skin rejuvenation.
One of the most popular anti-wrinkle peptides. Stimulates collagen and fibronectin production. Clinical studies show measurable wrinkle reduction after 2-4 months of use.
Advanced version combining palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. Targets multiple pathways of skin aging including collagen synthesis and inflammation reduction.
Known as "Botox in a jar" — inhibits neurotransmitter release to reduce expression lines. Less potent than Botox but non-invasive. Works best on fine lines around eyes and forehead.
Stimulates collagen synthesis by mimicking the body's own collagen-building signals. Often combined with other peptides for synergistic effects in anti-aging serums.
Related to GHK-Cu, this peptide variant is used in hair growth products and wound-healing formulations. May support hair follicle health and skin repair.
Oral peptide supplement derived from animal collagen. Research supports benefits for skin elasticity, hydration, and wrinkle reduction with consistent oral supplementation over 8-12 weeks.
Anti-inflammatory cosmetic peptide that reduces IL-6 secretion. Helps address inflammation-driven skin aging (inflammaging). Usually combined with other peptides.
Pentapeptide that works synergistically with Argireline to reduce expression wrinkles. Inhibits acetylcholine release at the neuromuscular junction.
Extended version of Argireline with potentially stronger wrinkle-relaxing effects. Targets SNARE complex to reduce muscle contractions that cause expression lines.
Disclaimer: Cosmetic peptide claims vary in evidence quality. While topical peptides are generally safe, results depend on formulation, concentration, and consistent use. This guide is for informational purposes only.