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Clinical research, emerging evidence & practical references

The Peptide
Encyclopedia

Explore 55 peptide profiles and hundreds of guides, from BPC-157 to Retatrutide. Find research, comparisons and calculation tools, with clinical findings distinguished from emerging evidence as our library review progresses.

55
Peptide Profiles
500+
In-Depth Guides
8
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Featured Peptides

In-depth profiles of the most researched and discussed peptides

BPC-157

Recovery & Healing

A 15-amino acid peptide derived from human gastric juice, extensively studied for its regenerative and protective properties across multiple tissue types.

healingrecoverygut healthtendon repair

GHK-Cu

Anti-Aging

A naturally occurring copper-binding tripeptide with powerful regenerative, anti-aging, and wound-healing properties backed by decades of research.

anti-agingskin healthcollagenwound healing

Retatrutide

Weight Loss

A next-generation triple agonist targeting GLP-1, GIP, and glucagon receptors, showing unprecedented weight loss results in clinical trials.

weight lossGLP-1GIPglucagon

Tirzepatide

Weight Loss

A dual GLP-1/GIP receptor agonist developed by Eli Lilly, FDA-approved for both Type 2 diabetes (Mounjaro) and obesity (Zepbound), showing up to 22.5% weight loss in trials.

weight lossGLP-1GIPdiabetes

Semaglutide

Weight Loss

The GLP-1 receptor agonist that started the weight loss drug revolution, FDA-approved as Ozempic (diabetes) and Wegovy (obesity), with proven cardiovascular benefits.

weight lossGLP-1diabetesFDA-approved

TB-500

Recovery & Healing

A synthetic version of a naturally occurring 43-amino acid peptide (Thymosin Beta-4) known for promoting cell migration, wound healing, and tissue repair.

healingrecoveryinflammationmuscle repair

Tesamorelin

Growth Hormone

An FDA-approved growth hormone-releasing hormone (GHRH) analog that stimulates natural GH production, primarily used for reducing visceral fat and improving body composition.

growth hormonevisceral fatbody compositionFDA-approved

AOD-9604

Weight Loss

A modified fragment of human growth hormone (amino acids 176-191) developed specifically for fat loss without the metabolic side effects of full HGH.

weight lossfat burninggrowth hormone fragmentmetabolism

MOTS-c

Anti-Aging

A 16-amino-acid mitochondrial-derived peptide studied for metabolic signaling, exercise responses and healthy aging, with encouraging animal findings and developing human research.

anti-aginglongevityexercise mimeticmetabolism

Sermorelin

Growth Hormone

A synthetic growth hormone-releasing hormone (GHRH) analog that stimulates the anterior pituitary to produce and release natural growth hormone, supporting muscle growth, fat loss, and anti-aging benefits.

growth hormoneGHRHmuscle growthanti-aging

Ipamorelin

Growth Hormone

A selective ghrelin receptor agonist that stimulates growth hormone secretion with minimal impact on cortisol or prolactin levels, offering a selective approach to GH optimization without some side effects of other secretagogues.

growth hormoneghrelin mimeticmuscle growthbody composition

CJC-1295

Growth Hormone

A long-acting growth hormone-releasing hormone (GHRH) analog with extended half-life through DAC (Drug Affinity Complex) modification, providing sustained pituitary stimulation for continuous growth hormone elevation.

growth hormoneGHRHlong-acting peptidemuscle growth

PT-141 (Bremelanotide)

Other

A melanocortin agonist peptide that stimulates sexual arousal and desire in both men and women, originally developed for sexual dysfunction treatment with benefits for libido, erectile function, and overall sexual wellness.

sexual healthsexual functionerectile functionlibido booster

Epithalon

Anti-Aging

Epithalon (Epitalon) is a four-amino-acid peptide studied for telomere biology, circadian signaling and aging. Cell and animal findings are promising; small human studies address specific biomarkers or retinal disease rather than demonstrating longer human lifespan.

anti-agingtelomerescellular healthlongevity

Thymosin Alpha 1

Recovery & Healing

An immune-modulating peptide extracted from thymic tissue that enhances T-cell development, immune function, and recovery by supporting thymic hormone production and optimizing immune surveillance.

immune healthimmune supportimmune functionthymus gland

Kisspeptin

Growth Hormone

A neuropeptide that stimulates GnRH and LH secretion, promoting testosterone and growth hormone production while supporting reproductive health, fertility, and sexual function through central endocrine regulation.

growth hormonetestosteronefertilityreproductive health

KPV Peptide

Anti-Inflammatory

KPV is a potent anti-inflammatory tripeptide derived from alpha-melanocyte-stimulating hormone (α-MSH). It modulates immune responses through melanocortin receptors and NF-κB pathway inhibition, making it valuable for gut health, skin healing, and systemic inflammation reduction.

kpv peptideanti-inflammatorygut healthskin healing

5-Amino-1MQ

Weight Loss

5-Amino-1MQ is a potent small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that promotes fat cell metabolism and weight loss. While technically not a peptide, it's commonly grouped with peptide therapeutics due to similar applications in metabolic optimization and body composition improvement.

5 amino 1mqNNMT inhibitorweight lossfat metabolism

Dihexa

Cognitive Enhancement

Dihexa is a cognitive-enhancing peptide derived from angiotensin IV that promotes synaptogenesis and enhances cognitive function. Developed at Washington State University, it activates the hepatocyte growth factor (HGF) and c-Met receptor pathway, potentially supporting memory, learning, and neuroprotection.

dihexa peptidecognitive enhancementmemorylearning

Selank

Nootropic

Selank is a synthetic, tuftsin-derived peptide with encouraging anxiety findings from small human studies. Researchers are also studying cognition, stress responses and immune signaling, with evidence ranging from clinical reports to animal and laboratory work.

nootropic peptideanxiolyticanxiety reliefcognitive enhancement

Semax

Nootropic

Semax is a synthetic peptide being studied for attention, memory and recovery after stroke. Small human studies report encouraging performance and rehabilitation findings, while animal research explores its effects on BDNF-related signaling.

nootropic peptideACTH fragmentcognitive enhancementneuroprotection

Cerebrolysin

Nootropic

Cerebrolysin is a porcine-derived peptide mixture studied in stroke recovery, traumatic brain injury and dementia. Some trials report encouraging recovery or cognitive findings, but results differ by condition and outcome.

nootropic peptideneuroprotectivebrain healthstroke recovery

DSIP

Nootropic

DSIP is a nine-amino-acid peptide investigated for sleep and stress-related effects. Small human studies include encouraging sleep findings and limited or neutral results; the evidence does not establish a standard sleep-treatment regimen.

sleep peptideinsomniasleep qualitycircadian rhythm

SS-31

Anti-Aging

SS-31 (elamipretide) is a cardiolipin-binding peptide studied for mitochondrial disorders and aging-related dysfunction. Its Forzinity formulation has a specific Barth syndrome indication; broader human studies have produced mixed results alongside encouraging experimental findings.

mitochondrial peptideanti-agingcardiovascular healthcellular energy

Snap-8

Skin & Beauty

Snap-8 (Acetyl Octapeptide-3) is a topical anti-wrinkle peptide that inhibits SNARE complex function, reducing facial muscle contractions that cause wrinkles. The peptide offers Botox-like anti-aging benefits without injections, making it ideal for topical skincare applications.

anti-wrinkle peptideskin peptidefacial agingSNARE complex

Noopept

Nootropic

Noopept (GVS-111) is a potent nootropic peptide that enhances cognitive function through NGF and BDNF stimulation, improving memory, learning, focus, and neuroprotection. The peptide offers cognitive enhancement superior to racetams with faster onset and lower dosages.

cognitive enhancermemory peptideNGF BDNFnoopept benefits

Melanotan II

Skin & Beauty

Melanotan II is a synthetic melanocortin receptor agonist peptide that stimulates melanin production and darkens skin without sun exposure. The peptide offers tanning benefits with potential side effects that require careful consideration.

tanning peptidemelaninsun protectionskin tanning

LL-37

Immune

LL-37 is the active human cathelicidin antimicrobial peptide that provides direct pathogen killing, immune system modulation, and wound healing support. The peptide enhances innate immune defenses and promotes tissue regeneration through multiple mechanisms.

antimicrobial peptideimmune defensewound healingll-37 benefits

Humanin

Anti-Aging

Humanin is a 24-amino acid mitochondrial-derived peptide that provides neuroprotection, supports metabolic health, and promotes longevity through multiple mechanisms. The peptide protects against age-related diseases and supports healthy aging.

anti-aging peptidemitochondrial peptideneuroprotectionhumanin benefits

Gonadorelin

Hormone

Gonadorelin is a GnRH analog peptide that stimulates testosterone production through natural pituitary-gonadal axis signaling. The peptide offers an alternative to exogenous testosterone for male hormonal optimization, fertility support, and TRT supplementation.

testosterone peptideGnRH agonisthormone optimizationtestosterone stimulation

GHRP-6

Growth Hormone

A potent growth hormone secretagogue that stimulates natural GH production through ghrelin receptor activation.

growth-hormonesecretagogueanti-agingperformance

GHRP-2

Growth Hormone

A potent GH secretagogue similar to GHRP-6 but with reduced appetite stimulation, offering selective growth hormone elevation.

growth-hormonesecretagogueanti-agingmuscle-growth

Hexarelin

Growth Hormone

A potent hexapeptide growth hormone secretagogue with faster onset than GHRP variants, designed for maximum GH stimulation.

growth-hormonesecretagogueanti-agingperformance

Follistatin-344

Muscle Growth

A myostatin inhibitor peptide that blocks myostatin's negative regulation of muscle growth, enabling rapid and substantial muscle development.

muscle-growthmyostatin-inhibitorstrengthperformance

IGF-1 LR3

Muscle Growth

A modified insulin-like growth factor variant with extended half-life and enhanced anabolic properties for comprehensive muscle and tissue growth.

muscle-growthigf-1strengthrecovery

MGF

Muscle Growth

A naturally-produced muscle growth factor derived from IGF-1 that is upregulated by mechanical stress, enhancing muscle repair and hypertrophy.

muscle-growthrecoverystrengthigf-1

Oxytocin

Peptide Therapy

A naturally-produced nonapeptide hormone affecting social bonding, stress response, and physical well-being with applications in therapy and wellness.

social-bondingstress-reliefwell-beingpeptide-hormone

Liraglutide

Weight Loss

A GLP-1 receptor agonist peptide (Saxenda/Victoza) that enhances satiety, reduces appetite, and supports sustainable weight loss.

weight-lossglp-1metabolismappetite-control

Dulaglutide

Weight Loss

A long-acting GLP-1 receptor agonist (Trulicity) with once-weekly dosing for weight loss and metabolic health support.

weight-lossglp-1metabolismappetite-control

Exenatide

Weight Loss

A GLP-1 receptor agonist (Byetta/Bydureon) with rapid onset for appetite control and sustainable weight loss management.

weight-lossglp-1metabolismappetite-control

Pinealon

Nootropic

A synthetic tripeptide nootropic that supports brain health, cognitive function, and neurological wellness through pineal gland support.

nootropicbrain-healthcognitive-enhancementneuroprotection

VIP

Peptide Therapy

Vasoactive intestinal peptide with neuroimmunomodulatory effects supporting respiratory health, inflammation control, and overall wellness.

immune-supportrespiratory-healthinflammation-controlwellness

MK-677

Growth Hormone

An oral growth hormone secretagogue that stimulates GH and IGF-1 production without affecting cortisol levels, used extensively in research for muscle growth and recovery.

growth hormoneIGF-1muscle growthoral

Mazdutide

Weight Loss

A dual GLP-1/glucagon agonist developed by Innovent Biologics for weight loss and metabolic improvement, combining appetite suppression with increased energy expenditure.

weight lossGLP-1glucagonmetabolic

Survodutide

Weight Loss

Boehringer Ingelheim's dual GLP-1/glucagon agonist in clinical development for weight loss, combining appetite suppression with increased energy expenditure.

weight lossGLP-1glucagondual agonist

Orforglipron

Weight Loss

Eli Lilly's oral non-peptide GLP-1 agonist offering convenient daily oral dosing for weight loss, providing an alternative to weekly injectable GLP-1 therapies.

weight lossGLP-1oralnon-peptide

Pemvidutide

Weight Loss

Altimmune's GLP-1/glucagon dual agonist peptide for weight loss and metabolic improvement, combining appetite suppression with increased energy expenditure.

weight lossGLP-1glucagondual agonist

CJC-1295 DAC

Growth Hormone

A modified growth hormone releasing hormone (GHRH) with Drug Affinity Complex modification, providing long-acting GH stimulation via subcutaneous injection.

growth hormoneGHRHlong-actingpeptide

Thymulin

Peptide Therapy

A naturally occurring thymic peptide hormone that regulates immune system development and function, studied for immune modulation and aging-related immune decline.

immune supportthymic peptideimmune agingimmunosenescence

FOXO4-DRI

Anti-Aging

A senolytic peptide that selectively targets and eliminates senescent cells, potentially reversing aging at the cellular level.

senolyticcellular senescenceagingcellular rejuvenation

Pentosan Polysulfate

Recovery & Healing

A semi-synthetic polysaccharide derived from beechwood that supports joint health, cartilage repair, and reduces inflammation for recovery and injury healing.

joint healthcartilage repairrecoveryanti-inflammatory

ARA-290

Recovery & Healing

An innate repair receptor (IRR) agonist peptide that activates cellular repair mechanisms, showing promise for neuropathic pain, tissue healing, and recovery.

tissue repairneuropathic paininnate repairrecovery

Collagen Peptides

Anti-Aging

Bioavailable collagen fragments derived from animal collagen protein, supporting skin health, joint function, gut integrity, and connective tissue quality.

collagenskin healthjoint healthgut health

Palmitoyl Pentapeptide-4

Skin & Cosmetic

A cosmetic peptide that stimulates collagen synthesis when applied topically, reducing wrinkles and improving skin firmness without injections.

anti-agingskin carecollagen stimulationtopical

Argireline

Skin & Cosmetic

A cosmetic peptide that mimics Botox-like effects by reducing facial muscle contractions, reducing wrinkles and expression lines topically without injections.

anti-agingskin carewrinkle reductiontopical

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