Ozempic Butt: Why GLP-1 Medications Affect Body Shape [2026]
Comprehensive exploration of how GLP-1 medications affect gluteal fat and muscle composition, body shape changes, prevention strategies through exercise, and cosmetic treatment options for maintaining or restoring gluteal appearance.
What is Ozempic Butt?
Ozempic butt, like Ozempic face, is colloquial terminology for a physical change that can occur with rapid weight loss from GLP-1 receptor agonist medications. The condition is characterized by sagging, flattening, loss of volume, or loss of definition in the gluteal region (buttocks) that develops as weight is lost.
While Ozempic face gained mainstream media attention due to high-profile celebrity examples, Ozempic butt is equally real and often more noticeable to the individual experiencing it. The appearance changes from a firm, lifted, well-defined posterior to a softer, flatter, sagging one—sometimes described colloquially as a "deflated" look.
Unlike facial changes, which affect the appearance of age and can be partially addressed with fillers and skin tightening, gluteal changes primarily involve loss of muscle mass and fat volume. The solutions involve either allowing time for muscle rebuilding through training or pursuing cosmetic procedures like fat grafting.
Gluteal Anatomy: Understanding How GLP-1 Affects the Glutes
To understand how weight loss affects the buttocks, it's helpful to understand gluteal anatomy.
Gluteal Muscles
The gluteal region consists of three primary muscles:
- Gluteus Maximus: The largest and most superficial muscle, responsible for hip extension (moving the leg backward) and providing the bulk and projection of the buttocks. It's one of the strongest muscles in the human body.
- Gluteus Medius: Sits on the upper outer buttock, responsible for hip abduction (moving the leg away from the body) and stabilizing the pelvis during walking. Provides upper gluteal fullness.
- Gluteus Minimus: Deepest of the three, assists the medius in hip abduction. Not visible but contributes to overall gluteal shape.
Gluteal Fat Deposits
Overlying and interspersed with these muscles are subcutaneous fat deposits (under the skin) and intermuscular fat (between muscle layers). The distribution and amount of gluteal fat varies dramatically by genetics and sex: women naturally carry more gluteal fat due to estrogen-driven fat distribution patterns, while men carry less fat and more muscle proportionally in the glutes.
Skin and Connective Tissue
The skin overlying the glutes is relatively thick but still capable of sagging if volume diminishes rapidly. Fascia (connective tissue) connects and supports the gluteal muscles and fat. When muscles shrink and fat is lost, this supportive tissue becomes redundant, leading to sagging.
Why Rapid Weight Loss Causes Gluteal Changes
Weight loss affects the glutes through two primary mechanisms: fat loss and muscle loss (catabolism).
Fat Loss from the Glutes
When you lose weight, your body mobilizes fat stores for energy. The location of fat loss is genetically predetermined through a process called "selective mobilization." You lose fat first from areas where you have abundant fat stores and last from areas where you have less.
For women, fat loss typically follows this pattern: face → breasts → limbs → abdomen → glutes and thighs (which are often the last areas). For men, the pattern is slightly different: face → trunk → limbs → lower abdomen and glutes.
The glutes, particularly in women, are often relatively resistant to fat mobilization due to hormonal factors (estrogen) and localized metabolic resistance. However, with significant weight loss (20%+ body weight), gluteal fat loss becomes substantial and visible.
Muscle Loss During Weight Loss (Catabolism)
Beyond fat loss, rapid weight loss can trigger muscle catabolism—the breakdown of muscle tissue for energy. This is particularly true when:
- Caloric deficit is severe: Large deficits (greater than 500-750 kcal/day) increase muscle loss risk
- Protein intake is insufficient: Protein is needed to maintain and build muscle; inadequate intake leads to muscle loss
- Resistance exercise is absent: Muscles are maintained and built in response to stimulus (weight training); without this signal, muscles atrophy
- Weight loss is rapid: Losing more than 1.5-2 pounds per week increases metabolic stress and muscle loss
GLP-1 medications excel at creating a caloric deficit through appetite suppression, but they don't protect muscle—they can actually promote muscle loss if not used strategically. The result: rapid weight loss with significant muscle catabolism, including in the glutes.
Skin Sagging
With loss of underlying fat and muscle, the skin—which is relatively inelastic, especially in older individuals—sags inward. The supportive tissue that once stretched tight over muscle and fat becomes slack, creating a flattened, deflated appearance.
Understanding Body Composition Changes During GLP-1 Weight Loss
Total weight loss on GLP-1 medications consists of several components: fat loss, muscle loss, water loss, and glycogen depletion. Understanding the ratio of these components explains why some individuals maintain better body shape than others.
Typical Composition of Weight Loss
In uncontrolled weight loss (diet without exercise), weight loss typically consists of:
- 70-75% fat loss
- 20-25% muscle loss
- 5% water and glycogen
With adequate resistance training and protein intake during weight loss, this shifts dramatically:
- 85-90% fat loss
- 10-15% muscle loss
- 5% water and glycogen
For someone losing 50 pounds without exercise, that's approximately 10-12 pounds of muscle. For someone with the same 50-pound loss but with training and protein, it's only 5-7 pounds of muscle. In the glutes, this difference is visually dramatic.
Metabolic Adaptation
During prolonged weight loss, your metabolism adapts by reducing energy expenditure (adaptive thermogenesis). This is partly why weight loss slows after the initial rapid phase on GLP-1s. This adaptation, while metabolically normal, doesn't directly affect gluteal changes—it affects overall weight loss trajectory.
Prevention: Exercise and Nutrition Strategies
The most effective way to prevent or minimize Ozempic butt is through proactive intervention during weight loss. Two pillars are critical: resistance training and adequate protein intake.
Resistance Training for Gluteal Preservation
Resistance training sends a signal to your muscles: "You are needed; maintain your size and strength." Without this signal (from weight training), muscles atrophy. With consistent training, muscles are preserved or even built despite a caloric deficit.
Most Effective Glute-Specific Exercises:
- Barbell Back Squat: Compound movement targeting quads and glutes heavily. 3-4 sets of 6-10 reps, 2-3 times weekly. Progressive overload (increasing weight) is essential.
- Romanian Deadlift (RDL): Hip hinge movement heavily targeting the posterior chain (glutes, hamstrings, lower back). 3 sets of 8-10 reps, 2 times weekly.
- Conventional or Sumo Deadlift: Compound lift emphasizing glute extension. 3-4 sets of 5-8 reps (heavier), 1-2 times weekly.
- Hip Thrust (or Smith Machine Hip Thrust): Isolation movement specifically targeting glute maximus. 3-4 sets of 8-12 reps, 2-3 times weekly. Provides maximal glute activation.
- Bulgarian Split Squats: Unilateral (single-leg) movement with one foot elevated on a bench behind you. Targets glutes and quads. 3 sets of 8-12 reps per leg, 2 times weekly.
- Cable Kickbacks or Glute-Focused Leg Press: Isolation movements targeting glutes. 3 sets of 12-15 reps, 1-2 times weekly.
- Walking Lunges (Barbell or Dumbbell): Dynamic glute-targeting movement. 3 sets of 10-12 reps per leg, 1-2 times weekly.
Programming Recommendations: Aim for 2-4 dedicated glute-focused workouts weekly. Each session should include at least one compound movement (squat, deadlift, hip thrust) and 1-2 accessory exercises. Progressive overload is essential: gradually increase weight, reps, or sets over weeks and months.
Protein Intake
Adequate protein is the building block for muscle maintenance and synthesis. During weight loss on GLP-1, appetite suppression makes eating sufficient protein challenging. Strategies to achieve adequate intake:
- Target Intake: 1.4-1.6 grams of protein per kilogram of body weight daily. For a 150-pound (68 kg) person, this is approximately 95-110 grams daily. For someone heavier, proportionally more.
- Protein Shakes: Whey protein powder, casein, or plant-based protein shakes are low-volume, high-protein options. A 25-30 gram protein shake is easier to consume when appetite is suppressed than a chicken breast meal.
- Prioritize Protein at Each Meal: Eggs, Greek yogurt, cottage cheese, lean meats, fish, legumes.
- Protein Timing: Consuming 20-40 grams of protein within 1-2 hours post-workout may optimize muscle protein synthesis, though total daily protein is more important than timing.
Caloric Deficit Management
While GLP-1 naturally creates a deficit through appetite suppression, you can optimize this for muscle preservation by avoiding excessive deficits. Aim to lose 1-1.5 pounds per week rather than 3+ pounds weekly. This slower pace preserves more muscle. If you're losing 3+ pounds per week on GLP-1, you might increase caloric intake slightly (or decrease dose if medically appropriate) to slow weight loss.
Sleep and Recovery
Adequate sleep (7-9 hours nightly) is essential for muscle protein synthesis and hormonal balance. Poor sleep impairs muscle recovery and increases cortisol, promoting muscle breakdown. Prioritize sleep quality during weight loss.
Treatment Options for Ozempic Butt
If you\'ve already experienced gluteal volume loss despite your best efforts, or if you\'re unwilling to wait for gradual muscle rebuilding, several cosmetic procedures can restore gluteal appearance.
Fat Grafting (Autologous Fat Transfer)
Mechanism: Fat is harvested from areas of excess (abdomen, flanks, thighs, back) via liposuction, purified, and injected into gluteal regions to restore volume and lift.
Procedure: Performed under general or regional anesthesia by a plastic surgeon. Typically 1-2 hours. Involves liposuction to harvest fat and multiple small injections into gluteal areas.
Results: Immediate improvement in volume and shape. Results stabilize after 3-6 months as transplanted fat "takes." 30-70% of grafted fat typically survives long-term (average ~50%), providing durable results. Some patients achieve permanent volume improvement with a single procedure; others require touch-ups.
Cost: $3,000-$8,000+ depending on extent of grafting, surgeon expertise, and geographic location.
Advantages: Natural appearance and feel because it's your own tissue; potentially permanent results; no risk of foreign material reactions; simultaneous improvement in areas from which fat is harvested (liposuction bonus).
Disadvantages: Surgical procedure; recovery time (1-2 weeks of bruising and swelling); results are somewhat unpredictable (fat survival varies); if weight is regained, grafted fat may enlarge unevenly; cost is high.
Brazilian Butt Lift (BBL)
BBL is essentially a specialized fat grafting procedure focused on reshaping the gluteal region. It combines liposuction from areas like the abdomen, flanks, and thighs with fat grafting to the buttocks to create enhanced volume, lift, and shape.
Results: More dramatic enhancement than standard fat grafting. Results similar to fat grafting (30-70% fat survival).
Cost: $4,000-$10,000+.
Note: BBL carried a reputation for higher complications (including rare fat embolism) in some high-volume practices historically, though improved techniques have reduced this risk significantly. Choose an experienced, board-certified plastic surgeon.
Dermal Fillers
Mechanism: Hyaluronic acid fillers (Juvederm, Restylane) or Sculptra (poly-L-lactic acid) can be injected into gluteal areas to add volume.
Results: Temporary improvement in volume and shape. HA fillers last 6-12 months; Sculptra lasts 2+ years as it stimulates collagen.
Cost: $1,000-$3,000+ per treatment session.
Advantages: Non-surgical; minimal downtime; reversible (HA can be dissolved if over-corrected).
Disadvantages: Temporary results requiring repeat treatments; expensive relative to results; risk of uneven distribution or lumping if injected improperly.
Gluteal Implants
Mechanism: Silicone implants similar to breast implants can be surgically placed within or under the gluteal muscles to add permanent volume.
Results: Permanent enhancement of volume and projection.
Cost: $5,000-$10,000+.
Note: Implants are less popular in modern cosmetic surgery than fat grafting due to higher complication rates (infection, extrusion, asymmetry, discomfort) and the superior aesthetic results of fat grafting. Most modern plastic surgeons prefer fat grafting.
Muscle Rebuilding Through Training
The most natural and longest-lasting solution is rebuilding gluteal muscle through resistance training. This is slow (6-12 months for substantial rebuilding) but doesn't require surgery or ongoing procedures.
Timeline: With optimal training (glute-focused 3-4 times weekly) and high protein intake, you can gain approximately 0.5-1 pound of muscle per month. Rebuilding 10 pounds of lost gluteal muscle would take 10-20 months.
Cost: Only expense is gym membership or equipment ($500-$2,000/year).
Advantages: Natural results; no surgery; improves overall strength and health; cost-effective long-term.
Disadvantages: Slow process; requires consistent, dedicated training; requires adequate nutrition; not suitable for those seeking rapid results.
Broader Body Composition Changes Beyond the Glutes
Ozempic butt is one manifestation of broader body shape changes during GLP-1 weight loss. Understanding these can help you prepare and plan treatment.
Breast Changes
Women often experience significant breast volume loss, particularly with weight loss exceeding 20% body weight. This can lead to deflation, sagging, and aesthetic dissatisfaction. Some women pursue breast augmentation or lift procedures post-weight loss. This should ideally be delayed until weight loss has stabilized (6-12 months into GLP-1 therapy).
Arm Sagging
Loss of fat and tone in the upper arms can lead to sagging and loose skin (bat wing appearance). Resistance training targeting triceps (dips, tricep dips, overhead presses) helps maintain arm tone. For severe sagging, an arm lift (brachioplasty) is a surgical option but carries scarring concerns.
Thigh and Leg Changes
Inner thigh and upper leg sagging is common with significant weight loss. Resistance training (lunges, leg presses, squats) helps maintain leg tone. Severe sagging may require a thigh lift procedure (surgical).
Abdominal Sagging
Significant weight loss from a previously obese state can leave loose abdominal skin. Some individuals pursue abdominal skin removal (tummy tuck, abdominoplasty) after weight loss stabilizes.
Hand and Neck Changes
Loss of subcutaneous fat in hands and neck makes veins and tendons more prominent, highlighting age spots and signs of aging. Sun protection and skincare help minimize appearance. Fillers or laser treatments can address age spots and skin texture.
How Ozempic Butt Compares to Other Body Shape Changes
Understanding how different body areas are affected helps you prioritize prevention or treatment:
| Body Area | Primary Loss (Fat vs. Muscle) | Visual Effect | Prevention | Treatment |
|---|---|---|---|---|
| Face | Fat loss | Gaunt, aged | Slow weight loss, skincare | Dermal fillers, fat grafting |
| Breasts | Fat loss | Deflation, sagging | Slow weight loss, supportive bras | Breast augmentation/lift |
| Glutes | Fat + muscle loss | Flat, sagging | Glute-targeted training, protein | Fat grafting, muscle rebuilding |
| Arms | Fat + muscle loss | Loose skin, reduced tone | Arm exercises, protein | Arm lift, muscle rebuilding |
| Thighs/Legs | Fat + muscle loss | Loose skin, reduced definition | Leg exercises, protein | Thigh lift, muscle rebuilding |
| Abdomen | Fat loss | Loose skin, sagging | Slow weight loss, core training | Tummy tuck, core training |
Sex Differences in Ozempic Butt
Men and women experience gluteal changes somewhat differently due to biological differences in fat distribution and muscle composition.
Women
Women naturally carry more gluteal fat due to estrogen-driven fat distribution. This means women often have more absolute gluteal fat to lose, making volume loss more pronounced. Additionally, women have smaller gluteal muscles on average than men. When combined fat and muscle loss occurs, women experience more dramatic sagging and projection loss.
However, women with well-developed glutes from consistent training experience less noticeable changes, and rebuilding through training is achievable.
Men
Men naturally carry less gluteal fat and more muscle. Weight loss in men often manifests as gluteal muscle atrophy and loss of tone/definition rather than dramatic volume loss. However, if protein intake is inadequate during GLP-1 weight loss, muscle loss can be substantial.
Men benefit significantly from gluteal-targeted resistance training during weight loss to preserve muscle definition.
Frequently Asked Questions
Frequently Asked Questions
Ozempic butt is the sagging, flattening, or loss of definition in the gluteal muscles and fat that can occur with rapid weight loss from GLP-1 medications. The gluteal region (buttocks) is composed of large muscles (gluteus maximus, medius, minimus) layered with subcutaneous fat. During rapid weight loss, both the subcutaneous fat and sometimes the muscles themselves shrink. Additionally, the skin loses elasticity and sags as volume diminishes. The result: a flattened, drooping appearance rather than the firm, rounded shape of a well-developed posterior. Unlike the face, where volume loss causes aesthetic concern due to aging appearance, butt deflation primarily affects the shape and projection of the gluteal region. It's particularly noticeable in individuals who previously had fuller or more prominent buttocks.
Both muscle and fat loss occur, though the ratio depends on several factors. GLP-1 medications suppress appetite dramatically, leading to reduced caloric intake. If you're consuming significantly fewer calories (1,200-1,500 kcal/day) without adequate protein and resistance exercise, your body breaks down muscle tissue for energy (catabolism). This is particularly true in the first few months of weight loss when caloric deficit is greatest. Muscle loss can account for 20-30% of total weight loss if protein intake and exercise are inadequate. Conversely, with adequate protein (1.2-1.6 g/kg body weight) and regular resistance training, you can minimize muscle loss to 10-15% of total weight loss. The glutes are particularly vulnerable to atrophy because they're large muscles that require consistent use and stimulus to maintain. If weight loss is rapid and exercise is absent, gluteal muscle loss is substantial. This is why resistance training, particularly exercises targeting the glutes (squats, deadlifts, lunges, hip thrusts), is critical for maintaining gluteal shape and size during GLP-1 therapy.
Yes, substantially. Targeted resistance training focused on the glutes can minimize muscle loss and maintain gluteal size and definition. Effective exercises include: barbell back squats (3-4 sets of 6-10 reps, 2-3x/week), Romanian deadlifts (3 sets of 8-10 reps), Bulgarian split squats, hip thrusts (3-4 sets of 8-12 reps), cable kickbacks, and leg press with foot placement targeting glutes. Progressive overload (gradually increasing weight or reps) is essential to signal to your muscles that they're needed. Additionally, adequate protein intake (1.4-1.6 g/kg body weight, or roughly 100-150 grams daily for most adults) provides amino acids for muscle protein synthesis. Some research suggests consuming 20-40 grams of protein within 1-2 hours post-workout optimizes recovery. Finally, maintain overall caloric balance as much as possible: try to lose weight at 1-1.5 pounds per week rather than 3+ pounds per week. This reduces the metabolic stress that drives muscle catabolism. Combining these strategies—progressive resistance training, high protein intake, and slower weight loss—can preserve or even build gluteal muscle during GLP-1 therapy.
It's not unavoidable with proactive intervention. Many individuals using GLP-1 medications while maintaining serious resistance training and adequate protein report minimal gluteal sagging. However, if you lose weight without exercise, gluteal atrophy is nearly inevitable. The challenge is behavioral: GLP-1 medications reduce appetite and increase satiety, making eating adequate protein challenging. Additionally, rapid weight loss can leave you fatigued, potentially reducing your motivation for rigorous exercise. Overcoming these barriers requires intentional effort: perhaps using protein shakes to reach protein targets, setting a structured training plan, and scheduling workouts as non-negotiable. That said, some gluteal volume loss is likely unavoidable if losing large amounts of weight (20%+ body weight) due to inherent fat loss. The goal is to minimize the aesthetic impact by maintaining muscle tone and size. Even if some volume is lost, well-developed, firm glutes are far more aesthetically appealing than flat, saggy ones.
Fat loss is genetically predetermined: you lose fat first from areas where you have the most, and last from areas where you have the least (or have hormonal/genetic resistance to mobilization). This is called "selective mobilization." For women, typically: face → breasts → limbs (arms, calves) → torso (abdomen) → thighs/butt. For men: face → trunk → limbs → lower abdomen. This explains why women on GLP-1 often lose breast volume and facial fullness early while retaining hip and thigh fat longer—these areas are hormonally resistant to fat mobilization in women. Conversely, men may lose abdominal fat before lower body fat. The buttocks are distributed differently between sexes: women have more gluteal fat, while men have more gluteal muscle. For women losing substantial weight, gluteal fat loss is often significant. For men, muscle loss in the glutes due to caloric deficit may be the primary problem. These patterns vary individually based on genetics. If you're prone to carrying fat in your glutes, it will be one of the last areas to mobilize, which can be beneficial aesthetically. If you carry minimal fat there, any loss will be noticeable.
Yes, you can rebuild gluteal muscle through resistance training, though it takes time and consistency. Muscle hypertrophy (growth) is a slow process: even with optimal training and nutrition, you might gain 0.5-1 pound of muscle per month. If you lost 5-10 pounds of gluteal muscle during GLP-1 weight loss, rebuilding it would take 5-10 months or longer. However, the timeline depends on several factors: your training experience, genetics, protein intake, and caloric balance. If you maintain a caloric surplus (eating slightly above maintenance) while training, you'll gain muscle faster than in a deficit. Progressive resistance training with progressive overload (gradually increasing weights) is essential. Most effective: compound movements (squats, deadlifts, hip thrusts) with 6-15 rep range, 3-4 sets per exercise, 2-3 times weekly. Additionally, hormonal status matters: testosterone and growth hormone support muscle growth; estrogen in women is less anabolic for muscle. Despite these differences, both sexes can substantially rebuild gluteal muscle with consistent training. The process is slower than muscle loss, but achievable.
Yes, several options exist for those unwilling to wait for natural muscle rebuilding or seeking faster results. Fat grafting (autologous fat transfer) is the most effective: fat is harvested from areas of excess (abdomen, flanks, thighs) via liposuction and injected into the buttocks to restore volume and lift. Results look and feel natural because it's your own tissue. Cost: $3,000-$8,000+. Alternatively, dermal fillers can be injected into the buttocks, though results are temporary (lasting 6-12 months) and expensive. Brazilian Butt Lift (BBL), a type of fat grafting, has become popular; however, it carries risks including fat embolism (though rare) and variable fat survival rates. Implants are another option but are less popular in modern cosmetic surgery due to higher complication rates compared to fat grafting. Sculptra (poly-L-lactic acid) injections can stimulate collagen and add subtle volume, lasting 2+ years. The most practical approach: combine resistance training with cosmetic procedures. Train to rebuild muscle while using fat grafting or fillers to restore volume, achieving optimal aesthetic results faster than training alone.
Most individuals notice visible gluteal flattening with 10-20% body weight loss. The timeline depends on the rate of loss: losing 20 pounds over 6 months rarely causes dramatic butt sagging, but losing 20 pounds in 6 weeks (rapid GLP-1 weight loss) commonly does. At 20-30% body weight loss, gluteal changes are usually pronounced: visible sagging, loss of projection, flattened contour. Conversely, some individuals notice minimal change because genetics and baseline gluteal composition vary: someone with naturally small glutes and minimal gluteal fat will see less obvious volume loss than someone with full, prominent glutes. Additionally, muscle mass influences visibility: someone with well-developed gluteal muscles may maintain good shape even with fat loss, whereas someone with minimal muscle development will appear more deflated. Age also matters: younger individuals with better skin elasticity may show less sagging despite volume loss, while older individuals with reduced elasticity may show more pronounced sagging at the same weight loss percentage.
GLP-1-induced weight loss affects the entire body, not just face and glutes. Other commonly affected areas include: breasts (significant volume loss, particularly in women, leading to sagging; supportive bras or surgical augmentation may be desired), inner thighs and upper legs (sagging skin, loss of firmness), arms (loose skin, reduced muscle definition), torso (loose abdominal skin if large amounts of weight lost), hands (prominent veins, visible age spots from sun exposure now more apparent due to lost hand fat), and neck (sagging, prominence of neck tendons and cords). The cumulative effect of whole-body fat loss is accelerated aging appearance. However, the same prevention strategies apply broadly: resistance training (particularly for areas with muscles—arms, legs, core), excellent skincare and sun protection, slow weight loss, adequate protein, and hydration. Cosmetic procedures for other areas (arm lift, breast lift or augmentation, thigh lift, abdominal skin removal) exist but are surgical and expensive. The most practical approach is prevention through the strategies mentioned.
Not unless appearance is your absolute top priority over health. The cardiovascular, metabolic, and longevity benefits of significant weight loss generally outweigh cosmetic concerns. Additionally, Ozempic butt is preventable or minimizable through proper exercise, nutrition, and slow weight loss. If you're concerned, discuss with your provider how to titrate GLP-1 slowly, and commit to a serious resistance training program (particularly glute-focused exercises) and adequate protein intake. Many individuals have successfully used GLP-1 medications while maintaining excellent gluteal development through consistent training. Alternatively, if you lose substantial volume despite best efforts, cosmetic procedures (fat grafting, fillers) can restore appearance. The combination of health benefits, preventive measures, and cosmetic options means Ozempic butt should not be a reason to avoid GLP-1 therapy. However, if you value aesthetic appearance highly, going into treatment with realistic expectations and a proactive plan (exercise, training, possible future cosmetic procedures) is wise.
Both sexes are affected, but in different ways. Women are more likely to experience visible gluteal fat loss because they naturally carry more gluteal fat (due to estrogen-driven distribution patterns). This fat loss leads to obvious volume loss, sagging, and loss of the rounded shape that's aesthetically valued in female body ideals. Men are more likely to experience loss of gluteal muscle definition and firmness, since men naturally carry less gluteal fat and more muscle. For men, maintaining glute muscle through resistance training becomes particularly important. Additionally, women may be more psychologically affected by gluteal changes because aesthetics and body image are often emphasized culturally. That said, body satisfaction is individual; some women prioritize health over appearance, and some men are very concerned with gluteal definition. The key point: both sexes benefit from resistance training and adequate protein during GLP-1 weight loss to preserve or rebuild the glutes.